and memory loss
Tricyclic antidepressants, such as amitriptyline, increase the availability of several neurotransmitters but also have anticholinergic effects. This makes them associated with a higher risk of dementia and cognitive impairment, particularly in older adults.
Today, safer alternatives such as selective serotonin reuptake inhibitors (SSRIs) are available and offer a better safety profile.
Statins and cognitive function
Statins, such as simvastatin, modify cholesterol, but their prolonged use can cause memory impairment and mental confusion. Some studies show an increased risk, while others indicate protection against dementia, showing attenuated
